Tesamorelin: A Stable Cousin of a Hormone Your Body Already Makes

Inside your brain, the hypothalamus releases a hormone called GHRH (growth hormone-releasing hormone). It tells the pituitary gland, "hey, time to release some growth hormone." The problem? Plain GHRH falls apart in your blood within minutes.

What Tesamorelin is

Tesamorelin is a synthetic version of GHRH with a small chemical modification on one end that makes it much more stable. Researchers can use it to study what happens when growth hormone release is steady and predictable, instead of vanishing in seconds.

What's been studied

Tesamorelin is one of the few peptides on this list that's gone through large clinical trials in humans. It received FDA approval in 2010 for a specific condition called HIV-associated lipodystrophy, where patients accumulate visceral (deep belly) fat. Studies showed Tesamorelin reduced this fat without major changes in subcutaneous (under-the-skin) fat.

Beyond that, researchers have looked at its effects on cognitive function, lipid profiles, and overall growth hormone signaling.

Why it matters in research

Most GHRH analogs in the lab are short-lived. Tesamorelin gives scientists a longer window to study downstream effects of stimulating the body's own growth hormone system, rather than injecting growth hormone directly.

Important: Tesamorelin is sold for laboratory and research use only. Even though it has approved clinical applications, our material is not intended for human treatment or consumption.